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PR-43-P Pharma Process Refractometer

Brand: K-Patents Process Instruments

K-Patents has applied its expertise to developing the unique and innovative Pharma process refractometer PR-43-P to measure, refine, manage and indicate liquid concentration or density and diagnostic information. 

The Pharma refractometer PR-43-P is designed to meet pharmaceutical industry standards and guidelines including PAT, GMP, CIP/SIP, 21 CFR Part 11 and validation. 

The Pharma PR-43-P system consists of a compact process refractometer and a graphical user interface. The PR-43-P has a measurement range of 0 to 100 Brix and provides an Ethernet or 4–20 mA output signal proportional to the temperature-compensated concentration value for real-time process control.

The user can choose between a rugged, multichannel, industrial computer or a compact light-weight user interface. 

The PR-43-P Refractometer has a built-in web server with an instrument homepage. The homepage enables the configuration, monitoring, verification and diagnosis of the refractometer via an Ethernet connection. 

Every PR-43-A Refractometer also generates an mA output signal for control purposes. The PR-43-P refractometer needs no recalibration or regular maintenance. Furthermore, the calibration of each refractometer can be verified using standard refractive index liquids and a built-in verification procedure.

Specifications

Accuracy

  • Across the Full Range of 0-100 Brix: Refractive Index ND ± 0.0002 Typically Corresponds to ± 0.1 Brix or % by Weight (Standard)
  • High Accuracy Version -HAC in the Range of 0-30 Brix & 4° to 30° C: ± 0.02 Brix or % by Weight (In Set-Point Applications)
  • High Accuracy Version -HAC in the Range of 0-30 Brix & 4° to 30° C: ± 0.05 Brix or % by Weight

Ambient Temperature Range

  • Compact User Interface CI: 0° to 50° C (32° to 122° F)
  • Multi-Channel User Interface MI: -40° to 50° C (-40° to 122° F)
  • Refractometer: -40° to 45° C (-40° to 113° F)

Calibration

  • With NIST Traceable Cargille Standard R.I. Liquids over Full Range

Current Output

  • Galvanic Isolation 1,000 Vdc or AC (Peak), Hold Function During Prism Wash
  • Isolated 4-20 mA - Max.

Digital Measurement

  • 3648 Pixel CCD Element

Enclosure

  • Compact User Interface CI: Epoxy Coated Enclosure with Polycarbonate Display Shield for Field Conditions
  • Compact User Interface CI: IP65, NEMA 4, Light-Weight Aluminum Enclosure for Laboratory & Control Room Conditions
  • Multi-Channel User Interface MI: Environmentally Sealed 316 Stainless Steel IP67, NEMA 6 Enclosure for Demanding Field, Outdoor & Laboratory or Control Room Conditions [-40° to 50° C (-40° to 122° F)]

Hygienic Design Certification

  • 3-A Sanitary Standard 46-03 Certified & EHEDG (European Hygienic Equipment Design Group) Typical El Class I Certified

Instrument Verification

  • With NIST Traceable Cargille Standard R.I. Liquids & Guided Procedure, Including A Printable Verification Report

Interconnecting Cable Length

  • 10 metres (Standard), Field-Adjustable with a Platform 4 Cable Extender for up to 100 metres

Light Source

  • Light Emitting Diode (LED), 589 Nm Wavelength, Sodium D-Line

Patented Core-Optics

  • No Mechanical Adjustments

Power Supply

  • Compact User Interface CI: 24 Vdc ± 10 %, 8.5 W, Max.
  • Multi-Channel User Interface MI: 24 Vdc, 60 W
  • Multi-Channel User Interface MI: AC Input 100-240 Vac / 50/60 Hz, 60 W
  • Refractometer: 24 Vdc ± 10 %, Max.

Process Connection

  • 2.5” I-Clamp
  • Sanitary 3A-Clamp 2.5”
  • Varivent In-Line Access Unit Clamp DN 65 or Via Elbow Flowcell (For Line Sizes of 2.5” & Smaller)

Process Pressure

  • Sanitary 3A & I-Clamp - High Pressure psi: 580.2 (kPa: 4,000, bar: 40) at 20° C (70° F)
  • Sanitary 3A & I-Clamp - Max.
  • Sanitary 3A & I-Clamp - psi: 125 (kPa: 900, bar: 9) at 120° C (250° F)

Process Temperature

  • -40° to 130° C (-40° to 266° F)

Process Wetted Parts

  • AISI 316L Stainless Steel
  • EHEDG Certified Process Connection Gasket for EHEDG Compliant Installation
  • Prism Gasket Modified PTFE(Teflon)
  • Prism Sapphire
  • Sanitary Process Connection Gasket EPDM for Sanitary 3A-Clamp

Refractive Index Range

  • Full Range, ND=1.3200 to 1.5300 (Corresponds to Hot Water to 100 Brix or % by Weight) (Standard)
  • nD = 1.2600 to 1.4700

Refractometer Protection Class

  • IP67
  • NEMA 6P (For Outdoor Use)

Remote & Ethernet Connection

  • 10/100Base-T Ethernet
  • UDP/IP Protocol Connection for Data Acquisition
  • Web Server for Configuration & Diagnostics

Repeatability

  • Across the Full Range of 0-100 Brix: ND ± 0.00004 (Typically Corresponds to ± 0.02 Brix or % by Weight)

Speed of Response

  • 1 second Undamped, Damping Time Selectable up to 5 minutes

Temperature Compensation

  • Automatic, Digital Compensation

Temperature Sensor

  • Built-In Pt-1000, Linearization According to IEC 751

User Interface Models

  • Compact User Interface CI
  • Multi-Channel User Interface MI
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